tag:blogger.com,1999:blog-1851682447163727760.post3150864845837238400..comments2023-09-08T06:11:33.395-07:00Comments on Women's Health and Fertility: New 2011 Study Questions Routine Metformin Use In All PCO Patientswomen:s health and fertilityhttp://www.blogger.com/profile/08894216102467479481noreply@blogger.comBlogger8125tag:blogger.com,1999:blog-1851682447163727760.post-68184328182159896532011-08-10T06:34:12.715-07:002011-08-10T06:34:12.715-07:00Hello Amy,
Thank you for your comments and for tak...Hello Amy,<br />Thank you for your comments and for taking the time to read my blog! Glad to hear that you have been able to manage your PCOS! <br /><br />I am always a little pressed for time, as you might imagine, but if you have a specific topic that you and your followers would like further clarification on re PCOS, I would be happy to write a short piece for you. I will email you the contact informtion. Have a good day!women:s health and fertilityhttps://www.blogger.com/profile/08894216102467479481noreply@blogger.comtag:blogger.com,1999:blog-1851682447163727760.post-76262575469330809242011-08-09T12:18:22.247-07:002011-08-09T12:18:22.247-07:00Dr. Ramirez - Thanks for your refreshing approach ...Dr. Ramirez - Thanks for your refreshing approach to managing PCOS. So many doctors take a cookie cutter approach. I took Metformin to conceive my second child. I swore I would never take it again after the GI issues I experienced. Since I concieved over 9 years ago I have been successfully managing my PCOS symptoms through diet and lifestyle change. So much so, I had a little "surprise" 2 years ago and now have a beautiful daughter. I share what I have learned and help coach women with PCOS to take on their health and life on www.pcosdiva.com and on facebook at www.facebook.com/pcosdiva. I would be thrilled if you would consider guest blogging on my site about this very topic. Please contact me at amy@pcosdiva.comamy Medlinghttp://www.pcosdiva.comnoreply@blogger.comtag:blogger.com,1999:blog-1851682447163727760.post-81013703192383700482011-08-04T19:52:49.601-07:002011-08-04T19:52:49.601-07:00Thank you for your response. When I first was face...Thank you for your response. When I first was faced with this quandary, I was concerned whether it might cause hypoglycemia, if I actually had no overt problems metabolizing glucose. Multiple sources had said this is not the case and one doctor had claimed that it can have a benefit even in non-insulin resistant individuals. I'm a scientist (an immunologist) myself, I have a good idea about how much variability there can be between studies, how little drug actions are understood, and how much in the dark everybody really is about the physiology of glucose metabolism. Everybody, at the end of the day, is just going with what we think is an informed opinion, but nobody has the right answer.<br /><br />I'm going to have to do a lot of reading on this before I decide one way or the other, but right now, I am leaning towards not taking metformin. Thank you for your input!Anonymoushttps://www.blogger.com/profile/15553205805046479504noreply@blogger.comtag:blogger.com,1999:blog-1851682447163727760.post-11663146192204191132011-08-03T09:38:13.424-07:002011-08-03T09:38:13.424-07:00Hello Jay,
I understand your dilemma and pain, ho...Hello Jay,<br /><br />I understand your dilemma and pain, however, I think your logic for using Metformin is not sound. Metformin is not a miracle drug for PCO patients. That is what the study showed. There is a down side. It is an insulin inhibitor, which means that if your insulin levels are normal and your cells are using it appropriately, the medication will deprive your body of adequate insulin. This will lead to higher glucose levels, altered metabolism and possibly diabetes. Metformin is NOT treating the PCO. It is meant to treat a condition that seems to be more prevalent on some PCO patients i.e. elevated insulin.<br /><br />So, although I do understand your desire to throw everything in to achieve a pregnancy and have a child, this is not only not reasonable, but may cause some harm. Treatments have to be specific for the problem that it is trying to treat. I would not recomend "crawling over glass" if it does nothing to help you get pregnant. On the other hand, if doing that does help you get pregnant, then I will certainly be the first to add that to my protocols.women:s health and fertilityhttps://www.blogger.com/profile/08894216102467479481noreply@blogger.comtag:blogger.com,1999:blog-1851682447163727760.post-13716064061864214742011-08-02T19:16:51.547-07:002011-08-02T19:16:51.547-07:00Thank you Dr. Ramirez for the information.Thank you Dr. Ramirez for the information.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-1851682447163727760.post-13488887048731759212011-08-01T17:43:50.601-07:002011-08-01T17:43:50.601-07:00Well this is a topic close to my heart! I'm so...Well this is a topic close to my heart! I'm somebody who is debating taking metformin very hard. I come from a family of type 2 diabetics, though both my fasting glucose was great and I passed the 2 hour GTT with flying colors. Yet,I have some presentations of PCOS: multicystic ovaries (AFC is over 30), high DHEAS, high AMH(5.1-5.6) and extremely mild hirsutism(my ferriman gallway score would be around 7-8). My testosterone is low, my FSH:LH ratio is perfect, I'm skinny, and ovulate regularly. I get pregnant with no medications, each time I've tried. I've also had 2 first trimester losses, the first time with a normal XY karyotype and the second time with Turner's syndrome.<br /><br />The other issues I have are low positive anti-thyroid antibodies and a vitamin D deficiency (now corrected). And the possible PCOS- I think I barely qualify by the Rotterdam Criteria.<br /><br />Nothing is clear cut with the research, but everybody seems to be utterly in the dark regarding the physiology of glucose metabolism and its relationship to infertility. My bottom line is that I want to leave no stone unturned and will do everything in my power to avoid a 3rd loss. If it involves taking metformin, how can it hurt? Yes it has unpleasant side effects and can deplete B12, but women would happily crawl over broken glass if it meant that they'd get a baby for it:(<br /><br />There is no evidence to show it does harm, does it?Anonymoushttps://www.blogger.com/profile/15553205805046479504noreply@blogger.comtag:blogger.com,1999:blog-1851682447163727760.post-58421355672237641332011-08-01T13:09:26.762-07:002011-08-01T13:09:26.762-07:00Hello,
I am sure that many many patients have bee...Hello,<br /><br />I am sure that many many patients have been treated the same.As the saying goes, "its spilled milk" so there is no sense in being upset about it. My hope is that it will make patients more diligent in questioning the expertise and qualifications of the doctors that they see so that they receive the best medical care. I am seeing a deterioration of that as more an more patients accept non-specialists for specialty care, and non-Physicians for their general health care. Ultimately, it is patients that drive the quality and availability of health care!women:s health and fertilityhttps://www.blogger.com/profile/08894216102467479481noreply@blogger.comtag:blogger.com,1999:blog-1851682447163727760.post-90814087354355477072011-08-01T10:20:05.279-07:002011-08-01T10:20:05.279-07:00My DR had previously put me on Metformin for my IF...My DR had previously put me on Metformin for my IF. She did not take my insulin levels or any other test. The only thing she could visibly see was I was overweight. Finally after being referred to an Infertility Clinic I was diagnosed with Polyps and after having them removed and doing IUI did acheive a positive pregnany result twice. Both times ended in miscarriage due to one polyp returning. But I still am upset at how the first DR just dismissed doing any tests and just told me to start taking the Metformin.Anonymousnoreply@blogger.com